Table 2.
Comparing retinal nerve fiber layer measurements between men and women with acute optic neuritis

Abbreviation: ON = optic neuritis.
Initial mean retinal nerve fiber layer measurement documented within 30 days of the acute optic neuritis event.
Repeated-measures analysis of variance statistical comparison.
Unpaired t test (a 2-sample [pooled or unequal variance] t test was used to compare men vs women).
Multivariate regression: effect of sex on retinal structural change at 6 months from baseline (adjusted for age, disease duration, use of disease-modifying therapy, use of high-dose corticosteroids for acute ON, and multiple sclerosis subtype [clinically isolated syndrome vs relapsing-remitting multiple sclerosis]).
Unaffected eyes of patients with optic neuritis.