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Hypoxia-selective interstrand cross-link formation by 1a upon UV-photolysis at 350 nm for 2 h under aerobic and anaerobic conditions. Phosphorimage autoradiogram of 20% denaturing PAGE analysis of the ICL product from duplexes containing 1a (6–9): Lanes 1, 4, 7, 10 and 13, DNA duplexes without UV irradiation; Lanes 2, 5, 8, 11 and 14, DNA duplexes irradiated under aerobic condition; Lanes 3, 6, 9, 12 and 15, DNA duplexes irradiated under anaerobic condition.
