Figure 3. Distribution of published studies on preventive therapy of household contacts of infectious TB patients, by geography, objective, and study setting.

Effectiveness studies relate to studies designed to address effectiveness as well as mixed effectiveness-efficacy for health-related outcomes, done in routine or mixed routine-research settings. Delivery studies relate to studies designed to address treatment completion and adherence, practices, and organization of services. Two non-comparative delivery studies were also included as effectiveness studies.