Table 3. Summary table of findings.
Summary of findings | ||||||
Differentia | Absoute effect | |||||
Category | Outcome concerned (n) | Quality assessment | Total number (n) | (±SD)d | Tol-DC(±SD)d | Control(±SD)d |
Different methods | imDC(1) | A(1A) | 15 | 128.40±0.00 | 150.00±0.00 | 13.80±2.70 |
imDC-alloAg(3) | A(3A) | 87 | 42.14±44.00 | 50.72±45.30 | 9.40±6.70 | |
Drug intervention(1) | A(1A) | 80 | 39.00±0.00 | 60.00±0.00 | 21.00±0.00 | |
MSC inducation(1) | A(1A) | 24–48* | 23.00±0.00 | 40.00±0.00 | 17.00±0.00 | |
Gene modification(4) | A(3A1C) | 80 | 8.99±4.75 | 18.09±7.58 | 9.12±3.43 | |
Other derivation(3) | A(2A1B) | 98 | 2.61±6.98 | 15.21±11.27 | 12.14±4.46 | |
Injection pathways | i.t.(3) | B(2A1B) | 66 | 58.62±60.81 | 67.66±56.00 | 9.21±1.93 |
i.v.(6) | A(6A) | 203 | 15.87±14.09 | 29.63±18.04 | 13.77±4.71 | |
i.p.(2) | A(2A) | 61 | 11.73±4.75 | 22.44±4.30 | 10.72±0.42 | |
s.c.(1) | C(1C) | -* | 6.50±0.00 | 10.50±0.00 | 4.00±0.00 | |
Does of DC | (S)104(1) | A(1A) | 21 | 90.00±0.00 | 100.00±0.00 | 10.30±1.10 |
(S)1–9×105(4) | A(3A1B) | 158 | 31.17±43.57 | 44.25±44.62 | 13.07±6.00 | |
(S)1–9×106(3) | A(3A) | 95–119* | 15.73±8.90 | 27.93±11.67 | 12.20±4.66 | |
(S)107(1) | A(1A) | 33 | 15.10±0.00 | 25.52±17.99 | 10.42±2.76 | |
(M)5×105(1) | C(1C) | -* | 6.50±0.00 | 10.50±0.00 | 4.00±0.00 | |
(M)107(1) | A(1A) | 28 | 8.38±0.00 | 19.38±9.81 | 11.00±1.58 | |
(M)2×107(1) | A(1A) | 19 | 9.00±0.00 | 20.00±9.39 | 11.00±1.14 | |
Animal model | Rat(4) | A(3A1B) | 110 | 45.30±51.42 | 54.12±53.14 | 8.82±1.73 |
Mouse(8) | A(7A1C) | 244–268* | 14.55±12.46 | 27.08±16.59 | 12.54±5.02 | |
Source of DC | Donor-Ag pulsed R-DC(3) | A(3A) | 87 | 61.73±48.44 | 71.16±49.94 | 9.43±1.50 |
Recipient-derived DC(3) | A(3A) | 132–156* | 23.46±15.32 | 39.79±20.31 | 16.33±5.03 | |
Donor-derived DC(5) | A(4A1B) | 126–150* | 9.28±11.55 | 21.46±14.32 | 12.18±3.70 | |
Donor-Ag pulsed D-DC(1) | A(1A) | 21 | −4.00±0.00 | 6.30±0.00 | 10.30±0.00 |
S: Single injection. M: Multiple injections.
“*” Sample size of one study is a range, not exact number. “-*” Article did not report sample size.