Figure 6. LPS-induced tumor-cell adhesion in the liver is prevented by treatment with edaravone (EDA). (A) Tumor cells in the livers of rats that were treated with PBS, EDA, LPS or LPS plus EDA. Rats were sacrificed 1.5 h after tumor-cell inoculation. Red: DiI-labeled CC531s cells, blue: cell nuclei, arrow heads point to CC531s cells (B) Quantification of the tumor cells in the livers of rats that were treated with PBS, EDA, LPS or LPS plus EDA. n = 4 per group; **p < 0.01; ***p < 0.001. (C) ZO-1 staining in the livers of rats that were either treated with PBS, EDA, LPS or LPS plus EDA. Green: ZO-1, blue: cell nuclei.