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. Author manuscript; available in PMC: 2013 Dec 15.
Published in final edited form as: Clin Cancer Res. 2012 Oct 10;18(24):6648–6657. doi: 10.1158/1078-0432.CCR-12-2715

Figure 1. Evaluation of siRNAs targeting the Type III fusion mRNA junctional sequence.

Figure 1

A. Western blot with anti-V5 antibody of 293T cells transfected with V5-tagged Type III fusion gene and, liposomes only (control), scrambled SiRNA in liposomes or one of four targeted siRNAs in liposomes. Tubulin is a loading control. B. Sequences of Type III targeted siRNAs are shown. The portion derived from the TMPRSS2 exon 1 is shown in green, while the portion from ERG exon 4 is shown in red.