Skip to main content
. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Bioorg Med Chem Lett. 2012 Nov 9;23(1):223–227. doi: 10.1016/j.bmcl.2012.10.132

Figure 1.

Figure 1

Structures of the M1 allosteric agonist TBPB (1), highlighting the key H-bond interaction with Thr83 for allosteric binding at M1, and analogs 2–5 of TBPB that retain selective M1 agonism.