Figure 5. Leading and lagging strand factors have reduced origin association in the absence of H2Bub1.
ChIP analysis of factors mediating leading and lagging strand DNA synthesis as described in Fig. 4 legend. A. DNA Polε; B. DNA Polα; C. PCNA; D. RPA. Error bars represent the standard deviation between two independent experiments (C, D) or from three technical replicates (A, B). IP signals were normalized as described in Fig. 4 legend.