Table 1.

Regulation of MMP Expression by Fox Transcription Factors

Fox Protein	MMP	Tissue or Cell Type	Reference
FoxC1	MMP7	Breast cancer tissue and breast cancer cell lines	(Sizemore and Keri, 2012)
FoxM1	MMP9	Human colorectal tissue samples, pancreatic cancer cells, papillary thyroid carcinoma, and breast cancer cell lines (MDA-MB-231 and SUM149)	(Ahmad et al., 2010; Ahmed et al., 2012; Uddin et al., 2011; Wang et al., 2010)
	MMP2	Glioma cells, oral cavity squamous cell carcinoma, and pancreatic cancer cells	(Chen et al., 2009; Dai et al., 2007; Wang et al., 2007)
FoxO3a	MMP9 MMP13	Cancer cell lines (HeLa and MDA-MB-435)	(Storz et al., 2009)
	MMP3	Endothelial cells (human umbilical vein endothelial cells)	(Lee et al., 2008)
FoxO4	MMP9	Rat aortic smooth muscle cells, COS cells, and C2C12 cells	(Li et al., 2007)