Table 3.
Event composition, power, and sample size estimates for the enriched subgroup and its complement
| Enriched Subgroup (n=75) |
Complement (n=350) |
Whole Sample (n=425) |
||||
|---|---|---|---|---|---|---|
| 10 year Cumulative Incidence (95% CI) |
Sample size for 80% power |
10 year Cumulative Incidence (95% CI) |
Sample size for 80% power |
10 year Cumulative Incidence (95% CI) |
Sample size for 80% power |
|
| Metastasis | 30% (15–47%) |
231 | 19% (13–25%) |
378 | 20% (15–26%) |
349 |
| Competing Mortality |
10% (3–24%) |
- | 21% (16–28%) |
- | 20% (15–26 %) |
- |
| Metastasis or Death |
40% (22–57%) |
313 | 40% (33–47%) |
835 | 40% 33–47%) |
709 |
CI = confidence interval.