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Cisplatin decreases levels of (a) the endocannabinoid 2-AG in rat hind paw skin without altering levels of (b) AEA relative to saline treatment. Levels of (c, d) fatty-acid amides (OEA, PEA) and (e,f) other inflammatory mediators (PGE2,PGF2α) were not altered in rat hind paw skin relative to saline treatment. Data are expressed as mean ± s.e.m. (n = 6–8 per group). * P < 0.029 vs. Saline (t-test, two-tailed).
