Figure 3.
Comparison of genes related to angiogenesis in white adipose tissue of C57 mice (n=8) and FVB mice (n=8) at 9 weeks of age on a chow diet. All genes displayed are differentially expressed between C57 mice and FVB mice (P<0.05). Significantly different growth factors (A), transcriptional factors (B), anti-angiogenic factors and matrix metalloproteinases (C), and two pro-angiogenic genes and three anti-angiogenic genes (D). Angpt1, angiopoietin 1; Col4a3, collagen type IV alpha 3 (tumstatin); Ctgf, connective tissue growth factor; Egf, epidermal growth factor; Epas1, endothelial PAS domain protein 1 (Hif-2alpha); Fgf1, fibroblast growth factor 1; Figf, c-fos induced growth factor (VEGF-D); Hgf, hepatocyte growth factor; Flt-1, FMS-like tyrosine kinase 1 (VEGFR-1); Igf1, insulin-like growth factor 1; Lect1, leukocyte cell derived chemotaxin 1; Mmp2, matrix metallopeptidase 2; Mmp9, matrix metallopeptidase 9; Mmp19, matrix metallopeptidase 19; Npr1, natriuretic peptide receptor 1; Pdgfa, platelet derived growth factor alpha; Pgf, placental growth factor; Ptgs1, prostaglandin-endoperoxide synthase 1 (Cox-1); Smad5, MAD homolog 5; Stab1, Stabilin-1; Tbx1, T-box 1; Tbx4, T-box 4; Thbs2, thrombospondin 2; Vegfa, vascular endothelial growth factor A.