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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Int J Obes (Lond). 2012 Sep 11;37(6):853–860. doi: 10.1038/ijo.2012.141

Figure 5. Differential expression of genes related to inflammation in white adipose tissue of C57 mice (n=8) and FVB mice (n=8) at 9 weeks of age on a chow diet. * P<0.05.

Figure 5

A) The expression of genes of markers for macrophage and recruitment of macrophage

B) Different polarization of macrophage in white adipose tissue of C57 mice and FVB mice. M1 and M2 mean the type of macrophage polarization. M1-type macrophages are more involved in pro-inflammation and recruitment of macrophage. M2-type macrophages are involved in tissue remodeling.

* P<0.05. Arg1, arginase; Ccl2, chemokine (C-C motif) ligand 2; Ccl3, chemokine (C-C motif) ligand 3; Ccr2, chemokine (C-C motif) receptor 2; Cxcl2, chemokine (C-X-C motif) ligand 2; Cd68, CD68 antigen; Emr1, egf-like module containing, mucin-like, hormone receptor-like 1; Ifng, interferon gamma; Il1b, interleukin 1, beta; Il6, interleukin-6; Itgax, integrin, alpha X (complement component 3 receptor 4 subunit); Jag1, jagged 1; Mgl2, macrophage galactose N-acetyl-galactosamine specific lectin 2; Tgfb, transforming growth factor, beta 1; Tnf, tumor necrosis factor