Skip to main content
. 2013 Jan;93(1):135–143. doi: 10.1189/jlb.0112025

Figure 3. Leukostasis is diminished in chimeric mice with circulating 5LO−/− leukocytes.

Figure 3.

The number of leukocytes adherent to the microvasculature or leukostasis was determined at 3 months of diabetes after perfusion with fluorescently labeled Con A. (A) Flat-mounted retinas were viewed via fluorescence microscopy, and brightly fluorescent leukocytes (yellow arrows) were counted in the entire retina. (B) The number of leukocytes adherent to the retinal microvasculature of the SD.WT and WT → SD.5LO−/− mice (black bars) was increased significantly compared with the retinas from ND control mice (white bars; *P<0.005) and 5LO−/− → SD.WT mice (gray bar; **P<0.05). Data represent six to eight mice.