Table 2.
Characteristics of lyso-PC micelles and the stability of the GpA TM helix dimer in different acyl-chain length lyso-PCs
| Lyso-PC | Cmc (mM) | MWapp (104 gmol−1) | Rh (Å) | Nagg SLS | Nagg Fluor. | ΔG°d (20 mM) (kJmol−1) | dΔG°d/dln(lyso-PC) (kJmol−1) |
|---|---|---|---|---|---|---|---|
| C10 | 6.06 (6.0–8.0) | 1.63 | 24 | 40 | 35 | 38.12 ± 0.48 | −4.75 ± 0.37 |
| C11 | 1.81 (—) | 3.55 | 26 | 67 | 58 | 34.61 ± 0.26 | −3.65 ± 0.25 |
| C12 | 0.57 (0.4–0.9) | 3.62 | 28 | 82 | 78 | 33.28 ± 0.52 | −3.45 ± 0.26 |
| C13 | 0.15 (—) | 4.45 | 30 | 98 | 91 | 32.34 ± 0.14 | −3.31 ± 0.11 |
| C14 | 0.04 (0.04–0.09) | 5.87 | 33 | 126 | 90 | 31.51 ± 0.11 | −2.92 ± 0.15 |
| C15 | 0.010 (—) | 8.80 | 34 | 183 | 100 | 28.38 ± 1.30 | −3.01 ± 0.11 |
| C16 | 0.004 (0.004–0.008) | 10.34 | 37 | 209 | 112 | 28.15 ± 1.44 | −2.96 ± 0.23 |
Values in parentheses were obtained from a commercial website (Avanti Polar Lipids, Alabaster, AL).