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. 2012 Dec;167(8):1596–1608. doi: 10.1111/j.1476-5381.2012.02059.x

Figure 7.

Figure 7

MAGL and non-MAGL components in the inhibition of 2-AG hydrolysis by α- and β-amyrin. (A) Concentration-dependent inhibition of purified hMAGL activity by α-amyrin, β-amyrin, pristimerin and JZL184. (B) Concentration-dependent inhibition of [3H]-2-AG hydrolysis in BV2 cell homogenate in presence of 1 µM URB597 and different concentrations of α-amyrin, β-amyrin, pristimerin, WWL70 and JZL184. Data show mean values ± SEM, n= 12 from four independent experiments. *P < 0.05, **P < 0.01 significantly different from vehicle control (=100%).