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Binding affinities on CB2 (Ki values) of four selected non virtual hits, the virtual hit 3, and the positive control (cannabinol)
| Compound | hCB2Ki ± SD [μM] | hCB1Ki/hCB2Ki |
|---|---|---|
| Cannabinol | 0.12 ± 0.01 μM | 0.42 ± 0.13 μM |
| 1 | > 100 | > 100 |
| 3 | 7.40 ± 0.60 μM | > 100 |
| 8 | > 100 | > 100 |
| 9 | > 100 | > 100 |
| 10 | > 100 | > 100 |
