FIG. 4.

qRT-PCR confirmation. qRT-PCR was performed to confirm the direction of fold change in expression (shown as log₂ fold change in human and mouse models by microarray). Human comparisons for Halb vs. Lalb (A), Lalb vs. ND (B), and Halb vs. ND (C) by qRT-PCR were compared with differential expression from microarray data. Mouse comparisons for DBA STZ vs. control (D), BKS db/db vs. control (E), and BKS eNOS^−/− db/db (F) were also compared with significant differential expression from microarray data. *P < 0.05.