FIG. 1.

Muscle-specific deletion of SOCS3 does not alter muscle development or performance. A: Tibialis anterior muscle histology (top) and quantification of muscle fiber cross-sectional area (CSA) (n = 3). B: Electron microscopy image (top) and quantification of mitochondrial content (right) in subsarcolemmal (SS) and intramyofibrillar (IMF) regions of tibialis anterior muscle (n = 3, scale bar = 2 µm, total = SS+IMF). C: Treadmill running capacity. D: Peak absolute force of tibialis anterior muscles (n = 7–10). All data were obtained from 10-week-old chow-fed male WT and SOCS3 MKO mice. (A high-quality color representation of this figure is available in the online issue.)