Table 3. Comparison of the Longitudinal Study of ICDs (LSICD) Cohort with a US National Sample of Primary Prevention ICD Recipients in 2006-2007.
Variable | LSICD | NCDR National | |
---|---|---|---|
| |||
N | 2621 | 110,455 | |
Age (yrs) at implant | 66.7 (11.6) | 67.7 (12.5)¶ | |
Female gender | 663 (25.3%) | 30014 (27.2%)∼ | |
Non-white race | 858 (32.7%) | 20925 (18.9%)¶ | |
History of heart failure | 2513 (95.9%) | 93717 (84.9%)¶ | |
NYHA Class | ¶ | ||
I | 299 (11.4%) | 8917 (8.1%) | |
II | 1235 (47.1%) | 38887 (35.3%) | |
III | 1026 (39.1%) | 57617 (52.2%) | |
IV | 55 (2.1%) | 5034 (4.6%) | |
LVEF (%) | 24.9 (6.9) | 25.1 (8.1) | |
Ischemic heart disease | 1670 (63.7%) | 72718 (65.8%)∼ | |
Previous CABG | 811 (30.9%) | 39615 (35.9%)¶ | |
Previous PCI | 799 (30.5%) | 35475 (32.1%) | |
Chronic lung disease | 508 (19.4%) | 24667 (22.3%)¶ | |
Diabetes | 1099 (41.9%) | 41936 (38.0%)¶ | |
Hypertension | 1916 (73.1%) | 82431 (74.6%) | |
Atrial fibrillation or flutter | 823 (31.4%) | 33759 (30.6%) | |
LBBB | 710 (27.1%) | 32289 (29.2%)∼ | |
Non-sustained VT | 366 (14.0%) | 23683 (21.4%)¶ | |
Creatinine (mg/dL) | 1.5 (2.9) | 1.4 (1.1) | |
Systolic blood pressure | 124.3 (20.3) | 129.77 (22.1)¶ | |
Medications | |||
ACE-inhibitor | 1739(66.6%) | 69231 (64.7%)¶ | |
ARB | 549 (21.0%) | 18542 (17.1%)¶ | |
Aspirin | 1756(67.3%) | 71542 (65.7%)∼ | |
Beta Blocker | 2385(91.4%) | 94777 (87.0%)¶ | |
Coumadin | 834 (32.0%) | 30563 (27.9%)¶ | |
Digoxin | 784 (30.0%) | 32229 (29.3%) | |
Statin | 2025(77.6%) | 68307 (62.3%)¶ |
Notes:
= p<0.05;
§ = p<0.01;
= p<0.001;
all continuous variables listed as means and standard deviations;
medications at discharge after ICD placement
Abbreviations: ACE=angiotensin converting enzyme; ARB=angiotensin receptor blocker; CABG=coronary artery bypass graftsurgery; LBBB=left bundle branch block; LVEF=left ventricular ejection fraction; NYHA=NewYork Heart Association; PCI=percutaneous coronary intervention; VT=ventricular tachycardia.