Table 1.

Binding affinity of 1–5

^aClosed circle and open circle indicate Im and Py, respectively.

^bΔG⁰ values are calculated from the equation, ΔG⁰ = −RTln (1/K_D), where R is universal gas constant, 1.987 cal/M•K; T is absolute temperature in a unit of K, here 298.15 K.