Table 1.
Gene-specific ChIP analysis was performed with an anti-FoxO1 or IgG
| Gene | Fold change | P-value |
|---|---|---|
| Dhrs9 | 6.01 | 0.0024 |
| Retsat | 4.94 | 0.0117 |
| Rbp1 | 3.79 | 0.0293 |
| Rdh8 | 3.87 | 0.0066 |
| Elk4 | 4.79 | 0.0000 |
| Midn | 4.21 | 0.0151 |
| Itpa | 1.76 | 0.0078 |
| Nr0b2 | 2.59 | 0.0035 |
| Txnip | 3.05 | 0.0001 |
| Pdk4 | 12.52 | 0.0015 |
| Pck1 | 6.34a | 0.0045 |
| Pck1 | 6.01b | 0.0024 |
| Rpl32 | 0.82 |
Twelve FoxO1-binding regions were randomly picked from ChIP-seq data, and the chromatin regions that harbor the FoxO1-binding site were amplified by qPCR using gene-specific primers. Results are expressed as fold change in comparison of DNA enriched by an anti-FoxO1 with that of IgG. Data represent the mean of triplicates.
a,bIndicate the peaks Pck1-a and Pck1-b, shown in Figure 2, respectively.