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Simulated Z-spectrum (a) and MTRasym (b) for a two-pool system (pa=0.99, pb=0.01) under the application of a spin-lock pulse (FSL=500Hz, TSL=50ms) at 9.4T when pool B resonates at different offset frequencies δb. (c) Variation of maximum MTRasym versus δb. (d) The location of maximum MTRasym approaches the exact offset frequency of pool B with increasing δb.
