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. 1979 Feb;15(2):243–245. doi: 10.1128/aac.15.2.243

In Vitro Activity of Rosamicin, Josamycin, Erythromycin, and Clindamycin Against β-Lactamase-Negative and β-Lactamase-Positive Strains of Neisseria gonorrhoeae

J W Biddle 1, Clyde Thornsberry 1
PMCID: PMC352640  PMID: 106776

Abstract

Randomly selected strains of β-lactamase-negative and β-lactamase-positive Neisseria gonorrhoeae were tested by an agar dilution method for susceptibility to rosamicin, josamycin, erythromycin, clindamycin, and penicillin G. Rosamicin was more active than erythromycin, which was more active than josamycin or clindamycin; the latter two were similar in their activity. The susceptibility to the macrolide antibiotics and clindamycin was independent of β-lactamase production, but the penicillin minimal inhibitory concentrations were higher in the β-lactamase-positive group because of the enzyme.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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