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. 2012 Nov 7;13:101. doi: 10.1186/1471-2350-13-101

Table 3.

Association between FTO (rs9939609), UCP-1 (rs6536991, rs2270565 and rs12502572) with obesity and Hardy-Weinberg equilibrium (HWE)

Genotype
 Patients
 Controls
 P
 OR
 95% CI
 HWE
  n % n %        
rs 9939609
  
  
  
  
  
  
  
  
TT
 34
 27
 41
 36
 0.04
 1
 -
 0.88
TA
 60
 48
 57
 50
  
 1.27
 0.71-2.27
  
AA
 32
 25
 15
 13
  
 2.57
 1.2-3.52
  
Allele
  
  
  
  
  
  
  
  
T
 128
 51
 139
 62
 0.02
 1
 -
  
A
 124
 49
 87
 38
  
 1.55
 1.07-2.23
  
rs6536991
  
  
  
  
  
  
  
  
TT
 10
 8
 17
 15
 <0.0001
 1
 -
 0.12
TC
 87
 69
 42
 37
  
 3.52
 1.48-8.35
  
CC
 29
 23
 54
 48
  
 0.91
 0.37-2.25
  
Allele
  
  
  
  
  
  
  
  
T
 107
 42
 76
 34
 0.046
 1
 -
  
C
 145
 58
 150
 66
  
 0.69
 0.47-1.0
  
rs2270565
  
  
  
  
  
  
  
  
TT
 109
 87
 104
 92
 0.25
 1
 -
 0.35
TA
 16
 13
 9
 8
  
 1.70
 0.72-4.01
  
AA
 1
 1
 0
 0
  
 2.968e+007
 1109e+007-7943e+007
  
Allele
  
  
  
  
  
  
  
  
T
 234 93
 217 96
 0.13
 1
 -
  
  
  
A
 18 7
 9 4
  
 1.86
 0.82-4.21
  
  
  
rs12502572
  
  
  
  
  
  
  
  
GG
 40 32
 46 41
 0.35
 1
 -
 0.49
  
  
GA
 61 48
 47 42
  
 1.49
 0.84-2.64
  
  
  
AA
 25 20
 20 18
  
 1.44
 0.70-2.97
  
  
  
Allele
  
  
  
  
  
  
  
  
G
 141 56
 139 62
 0.22
 1
 -
  
  
  
A 111 44 87 38   1.26 0.87-1.81