Table 5.
Clinical and laboratory dataa (UCP-1 rs6536991 genotype)
| Age (years) | Weight (Kg) | Height (cm) | Waist (cm) | BMI (kg/m2) | HDL (mg/dl) | LDL (mg/dl) | TG (mg/dl) | SBP (mmHg) | DBP (mmHg) | Fasting Glucose (mg/dl) | |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Obese |
|
|
|
|
|
|
|
|
|
|
|
| TT |
40.5±9.5 |
124.2±29.4 |
164.3±10.1 |
124.6±17.5 |
45.6±7.8 |
47.2±6.2 |
113.1±30.1 |
142.1±48.1 |
131±8.7 |
83.5±6.7 |
98.5±15.8 |
| |
(33.7-47.3) |
(103.2-145.2) |
(157.1-171.5) |
(112.1-137.1) |
(40–51.2) |
(42.7-51.7) |
(91.6-134.6) |
(107.7-176.5) |
(124.7-137.3) |
(78.7-88.3) |
(87.2-109.8) |
| TC |
39.8±12.6 |
114.6±20.9 |
163.6±8.8 |
119.7±12 |
42.6±5.8 |
50.6±13.2 |
119.6±35.7 |
154.0±96.7 |
137.4±14.1 |
87.2±8.7 |
107.7±48.6 |
| |
(37.1-42.5) |
(110.2-119.1) |
(161.8-165.5) |
(117.1-122.3) |
(41.4-43.8) |
(47.8-53.5) |
(111.8-127.4) |
(132.8-175.1) |
(134.4-140.4) |
(85.3-89) |
(97.1-118.3) |
| CC |
41.9±14.2 |
113.0±20 |
162.4±8.9 |
116.5±14.7 |
42.7±4.7 |
54.4±10.7 |
129.3±32.1 |
145.4±85.7 |
133.4±14.5 |
85.7±8.9 |
98.9±23.2 |
| |
(36.5-47.3) |
(105.4-120.6) |
(159–165.8) |
(111–122.1) |
(40.9-44.5) |
(50.1-58.6) |
(116.6-142) |
(112.2-178.7) |
(127.9-138.9) |
(82.3-89.1) |
(89.9-107.9) |
|
Control |
|
|
|
|
|
|
|
|
|
|
|
| TT |
51.2±16.3 |
64.0±9.7 |
161.0±6.1 |
85.8±11.2 |
24.7±3.4 |
54.8±15 |
134.1±39.1 |
127.5±52.4 |
135.7±21.7 |
81.6±6.3 |
80.0±12.6 |
| |
(42.9-59.6) |
(59–69) |
(157.8-164.2) |
(78.6-93) |
(22.9-26.4) |
(46.1-63.5) |
(111.5-156.7) |
(97.2-157.8) |
(124.5-146.9) |
(78.4-84.9) |
(72.7-87.2) |
| TC |
52.1±15 |
58.0±9.7 |
158.4±8 |
81.2±17.8 |
23.0±3.1 |
42.3±11.4 |
133.4±35.8 |
157.6±67.7 |
134.2±17.8 |
83.3±9.2 |
91.1±27.3 |
| |
(47.5-56.8) |
(55–61.1) |
(155.9-160.9) |
(77.5-84.9) |
(22.1-24) |
(38.3-46.2) |
(121.6-145.2) |
(135.3-179.8) |
(128.7-139.8) |
(80.4-86.2) |
(82.1-100.1) |
| CC |
48.0±19.3 |
56.6±10.7 |
161.6±9.8 |
74.4±11.6 |
21.7±3.5 |
49.3±16.4 |
113.1±25.6 |
110.4±59.5 |
126.9±15.7 |
80.1±9.1 |
89.3±14.9 |
| (42.7-53.3) | (53.7-59.5) | (158.9-164.2) | (70.6-78.2) | (20.7-22.6) | (43.8-54.9) | (104.4-121.8) | (90.3-130.5) | (112.7-131.2) | (77.6-82.6) | (84.4-94.2) |
aData shown as average ± SD and 95% confidence interval of the mean; bBMI, Body Mass Index; cHigh Density Lipoprotein; dLDL, Low Density Lipoprotein; eTG, Triglycerides; fSBP, Systolic Blood Pressure; gDBP, Diastolic Blood Pressure. TT denotes homozygous carriers of the T allele, TC heterozygous carriers, and CC noncarriers of UCP-1 rs6536991.