Table 1. The protein targets and the antigens used in the study.
Gene | Description | Mw for protein target (kDa) | No of aa for antigen | No of immunizations | Epitope mapping |
1. HNRNPH2 | Heterogeneous nuclear ribonucleoprotein H2 | 49,3 | 115 | 3 (2) | SP+BD |
2. SYNJ2BP | Synaptojanin 2 binding protein | 15,9 | 112 | 3 | SP+BD |
3. RPS6KA5 | Ribosomal protein S6 kinase, 90 kDa, polypeptide 5 | 89,9 | 136 | 3 | SP+BD |
4. ERBB2 | Erythroblastic leukemia viral oncogene homolog 2 (Her2) | 137,9 | 96 | 3 | SP+BD |
5. TYMP | Thymidine phosphorylase | 50,4 | 125 | 3 | SP+BD |
6. PDXP | Pyridoxal (vitamin B6) phosphatase | 31,7 | 137 | 3 | SP+BD |
7. FBXO28 | F-box protein 28 | 41,1 | 101 | 3 | BD |
8. C22orf29 | Chromosome 22 open reading frame 29 | 39,3 | 125 | 3 | BD |
9. FOXP2 | Forkhead box P2 | 79,9 | 104 | 3 | BD |
10. IL17RA | Interleukin 17 receptor A | 96,1 | 128 | 3 | BD |
Gene name and description of protein targets are listed as denoted by ENSEMBL. The molecular weight (kDa) of the protein target is shown. If several splice variants, the isoform with the largest molecular weight is shown. Further, the number of amino acids of the antigen (PrEST) is shown. The number of immunizations and the method of epitope mapping used in each cases is finally listed, with SP representing synthetic peptides using the suspension bead array method and BD representing bacterial surface display using gene fragment expressed on the surface of Staphyloccoccus carnosus cells.