Table 3. Crude and adjusted odds ratios for factors fostering treatment adherence among patients on anti-TB drugs (N = 645).
IsoScreen | Univariate analysis | Multivariate analysis | ||||||
Positive (%) | Negative (%) | OR | 95% CI | p-value | OR | 95% CI | p-value | |
Sex | ||||||||
Male | 351 (94.9) | 19 (5.1) | 1 | – | – | 1 | – | – |
Female | 266 (96.7) | 9 (3.3) | 2.04 | 0.78–5.30 | 0.145 | 1.94 | 1.24–3.02 | 0.003 |
Age (years) | ||||||||
18–24 | 82 (95.3) | 4 (4.7) | 1 | – | – | 1 | – | – |
25–34 | 196 (96.1) | 8 (3.9) | 1.69 | 0.42–6.81 | 0.457 | 1.74 | 0.60–5.01 | 0.300 |
35–44 | 170 (94.4) | 10 (5.6) | 0.85 | 0.22–3.28 | 0.817 | 0.77 | 0.59–0.99 | 0.049 |
≥45 | 169 (96.6) | 6 (3.4) | 1.72 | 0.41–7.24 | 0.460 | 2.15 | 0.82–5.66 | 0.120 |
Type of TB | ||||||||
Smear-negative pulmonary TB | 214 (95.1) | 11 (4.9) | 1 | – | – | |||
Smear-positive pulmonary TB | 279 (95.5) | 13 (4.5) | 0.95 | 0.36–2.47 | 0.919 | |||
Extra pulmonary TB | 124 (96.9) | 4 (3.1) | 2.30 | 0.65–8.03 | 0.198 | |||
Treatment phase | ||||||||
Intensive | 306 (95.6) | 14 (4.4) | 1 | – | – | |||
Continuation | 311 (95.7) | 14 (4.3) | 1.19 | 0.50–2.83 | 0.693 | |||
HIV and antiretroviral therapy status | ||||||||
HIV negative | 351 (95.9) | 15 (4.1) | 1 | – | – | |||
HIV positive on antiretroviral therapy | 199 (95.7) | 9 (4.3) | 0.99 | 0.37–2.60 | 0.976 | |||
HIV positive not on antiretroviral therapy | 67 (94.4) | 4 (5.6) | 0.88 | 0.25–3.18 | 0.851 | |||
Perceived side effect | ||||||||
No | 434 (95.8) | 19 (4.2) | 1 | – | – | |||
Yes | 182 (95.3) | 9 (4.7) | 0.98 | 0.89–1.01 | 0.785 | |||
Relationship of supporter | ||||||||
Non-family member | 187 (96.4) | 7 (3.6) | 1 | – | – | |||
Family member | 203 (94.4) | 12 (5.6) | 0.70 | 0.24–2.13 | 0.538 | |||
Spouse | 202 (96.7) | 7 (3.3) | 1.62 | 0.48–5.50 | 0.437 | |||
Missing | 25 (92.6) | 2 (7.4) | 0.75 | 0.14–4.18 | 0.747 | |||
Residence of supporter | ||||||||
Same house | 471 (95.9) | 20 (4.1) | 1 | – | – | 1 | – | – |
Neighbour | 131 (97.0) | 4 (3.0) | 1.65 | 0.49–5.57 | 0.420 | 1.38 | 0.77–2.47 | 0.284 |
>15 minutes walk | 15 (78.9) | 4 (21.1) | 0.08 | 0.022–0.29 | <0.001 | 0.08 | 0.02–0.25 | <0.001 |
Information prior to the visit | ||||||||
Announced | 414 (95.8) | 18 (4.2) | 1 | – | ||||
Non-announced | 203 (95.3) | 10 (4.7) | 0.86 | 0.36–2.09 | 0.744 | |||
Last dose observed by supporter | ||||||||
No | 138 (91.4) | 13 (8.6) | 1 | – | – | |||
Yes | 479 (97.0) | 15 (3.0) | 1.09 | 0.99–1.19 | 0.053 | |||
Setting | ||||||||
Non-pilot | 301 (91.6) | 24 (7.4) | 1 | – | – | 1 | – | – |
Pilot | 316 (98.8) | 4 (1.2) | 3.82 | 1.05–13.97 | 0.043 | 3.65 | 0.65–20.39 | 0.141 |
Location | ||||||||
Urban | 308 (96.6) | 11 (3.4) | 1 | --- | – | |||
Rural | 309 (94.8) | 17 (5.2) | 0.95 | 0.86–1.05 | 0.302 |