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. Author manuscript; available in PMC: 2012 Dec 19.
Published in final edited form as: Mol Cancer Res. 2009 Jun 2;7(6):863–869. doi: 10.1158/1541-7786.MCR-08-0418

Figure 4. MDM2-A enhances transformation in the absence of p53.

Figure 4

(A) Histogram of foci/78.5 cm2 formed in p53 null or Mdm2-a/p53-null MEFs (mean of 3 with standard deviation). (B) Micrographs of p53 null (upper) and Mdm2-a/p53-null (lower) foci at 4× magnification. Arrows point to examples of the observed foci.