Table 3.
Known links between xenobiotics, members of the gut microbiota, and key reactions. See Figures 1 and 2 for more information.
| Xenobiotic compound | Metabolizing isolate(s) | Reaction | Reference |
|---|---|---|---|
| Digoxin | Eggerthella lenta | Reduction reaction | [48] |
| Irinotecan | Bacteroides, Clostridium, Escherichia | Deconjugation | [10] |
| Levamisole | Bacteroides, Clostridium | Thiazole ring-opening | [127] |
| Sorivudine | Various Bacteroides: B. vulgatus, B. thetaiotaomicron, B. fragilis, B. uniformis and B. eggerthii | Phosphorylase activity | [133] |
| Sulfasalazine | Many genera including: Bacteroides, Bifidobacterium, Lactobacillus, and Enterococcus | Azoreductase activity | [50] |