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SOD activity in brain structures during cocaine (coc) self-administration (SA) by yoked-triad procedure. Data shown as a % of control ± SEM; *p < 0.05, ***p < 0.0001 versus yoked saline (sal); # p < 0.05, ### p < 0.001 versus yoked cocaine. In control (yoked saline) rats, the absolute SOD activity was 7.64 ± 0.28 U/mg protein in the hippocampus, 4.03 ± 0.39 U/mg protein in the frontal cortex and 6.32 ± 0.48 U/mg protein in the dorsal striatum. N = 6–8 rats/group
