Figure 5.

Comparison of Targets of the Core Exosome and Rrp6

(A) Proportion of sequences corresponding to functional RNA classes recovered with core exosome subunits (Rrp44, Rrp41, Csl4), and Rrp6. Sequencing data was analyzed as in Figure 1.

(B) Heat maps for main non-protein coding RNA substrate groups recovered with the indicated IP. Numbers of reads mapped to individual RNAs are shown in shades of red.

(C) Read coverage along highly structured RNAs (top) the U2 snRNA (LSR1; 1175nt); (middle) pre-tRNA^Pro_UGG (102nt, intron 37-66nt) and (bottom) the box C/D snoRNA snR40 (97nt).