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Potential mechanisms by which HIV may influence hepatocyte cell function and / or HCV replication. IL-8, interleukin 8; IFNα, interferon α; HCV, hepatitis C virus; STAT1, signal transducer and activator of transcription 1; FasL, fas ligand. Soluble HIV proteins include Tat (transactivator protein) and gp120 (envelope glycoprotein 120).
