Table 1.
Respiratory and ventilator parameters following 6 weeks of high-pressure and high-intensity noninvasive ventilation
| High pressure NIV (PSV) | High intensity NIV (PCV) | Mean difference (95% CI) | P value | |
|---|---|---|---|---|
| Mean nightly use (hours:minutes) | 6:37 ± 1:45 | 6:33 ± 2:14 | 0:04 (−0:45 to 0:53) | 0.851 |
| pH | 7.38 ± 0.01 | 7.38 ± 0.02 | 0.00 (−0.01 to 0.01) | 0.818 |
| PaCO2 (kPa) | 7.2 ± 0.8 | 7.0 ± 0.8 | 0.3 (−0.2 to 0.7) | 0.190 |
| PaO2 (kPa) | 7.9 ± 1.5 | 8.2 ± 1.3 | −0.3 (−0.7 to 0.03) | 0.070 |
| Serum bicarbonate (mmol/L) | 31 ± 4 | 30 ± 4 | 1 (−0.1 to 2.1) | 0.071 |
| Overnight mean tcCO2 (kPa) | 6.5 ± 1.2 | 6.5 ± 1.3 | −0.1 (−0.9 to 0.9) | 0.985 |
| Patient triggering rate (%) | 90 ± 9 | 25 ± 11 | 65 (51 to 79) | <0.001 |
| Bf (bpm) on ventilator | 14 ± 3 | 16 ± 2 | −2.6 (−1.4 to −3.7) | 0.002 |
Abbreviations: Bf, breathing frequency; CI, confidence interval; PaO2, arterial partial pressure of oxygen; PaCO2, arterial partial pressure of carbon dioxide; NIV, noninvasive ventilation; PSV, pressure support ventilation; PCV, pressure-controlled ventilation; tcCO2, transcutaneous carbon dioxide.