Table 3.
Side effects | AD-naïve | Overall | NMD | MD | BD |
---|---|---|---|---|---|
|
|
|
|
|
|
n = 80 | n = 71 | n = 35 | n = 17 | n = 19 | |
Sleepiness | 13.75 | 61.97** | 71.43 | 58.82 | 47.37 |
Malaise | 5.00 | 39.44** | 42.86 | 47.06 | 26.32 |
Dry mouth | 8.75 | 76.06** | 80.00 | 88.24 | 57.89 |
Constipation | 11.25 | 69.01** | 54.29 | 52.94 | 110.53 |
Dysuria | 3.75 | 36.62** | 31.43 | 52.94 | 31.58 |
Dizziness | 5.00 | 49.30** | 34.29 | 29.41 | 94.74 |
Cephalalgia | 5.00 | 28.17** | 22.86 | 35.29 | 31.58 |
Hidrosis | 2.50 | 15.49** | 17.14 | 11.76 | 15.79 |
Anorexia | 3.75 | 9.86* | 11.43 | 11.76 | 5.26 |
Tremor | 0.00 | 8.45 | 8.57 | 5.88 | 10.53 |
Akathisia | 0.00 | 5.63 | 5.71 | 5.88 | 5.26 |
Notes: Values are expressed as % of the total number of patients in each group;
P < 0.05,
P < 0.01 versus antidepressant-naïve patients (Mann–Whitney U test).
Abbreviations: AD, antidepressant; MD, melancholic depression; NMD, nonmelancholic depression; BD, bipolar depression.