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. Author manuscript; available in PMC: 2012 Dec 20.
Published in final edited form as: J Neurochem. 2010 Apr 16;114(1):271–280. doi: 10.1111/j.1471-4159.2010.06749.x

Fig. 4.

Fig. 4

Attenuation of lipid peroxidation–derived 4-hydroxynonenal (4-HNE) (a) and protein nitration-related 3-nitrotyrosine (3-NT) (b) in mitochondria by U-83836E at 12 h following controlled cortical impact traumatic brain injury in male mice. Animals were administered 3 mg/kg of U-83836E i.v. 15 min post-injury and oxidative markers were measured 12 h following injury. The levels of 4-HNE and 3-NT were detected using western blotting, (c) and (d) respectively. Lanes were loaded with either sham (S), vehicle (V), U-83836E (U) or loading control (LC). Values = mean ± SD. Statistical differences (one-way anova and Student-Neuman–Keuls post hoc test): *p < 0.001 versus sham, #p < 0.001 versus vehicle, @ p < 0.05 versus vehicle n = 10.