Twin B displays stage III ADNIV at the age of 49 years. (A) Fundus drawings record less severe epiretinal membrane and cystoid macular edema only OD. There was fibrotic vitreous traction at the disc and a fibrotic membrane over the pars plana OD. The peripheral retina showed pigmentary and atrophic changes. There were vitreous cells and vitreous bands OU. (B) Fundus photograph OD shows an epiretinal membrane and cystoid macular edema. At the optic disc there was fibrous traction (arrowhead) and pigmentary changes (arrow). (C) Fundus photograph OS shows asteroid in the vitreous. (D) Optical coherence tomography OD shows cystoid macular edema. (E) There was no cystoid macular edema OS.
Abbreviations: ADNIV, autosomal dominant neovascular inflammatory vitreoretinopathy; OD, right eye; OS, left eye; OU, both eyes.