(b).
The enhancement factors, E B and E I, obtained using the two different metrics.†
| Enhancement factor (a.u.) | E B | E B | E I |
|---|---|---|---|
| Metric used in reanalysis | B rel5 | B relDS | I/I 0 |
| HEWL + Nitrate I | 1.53 | 1.18 | 1.44 |
| HEWL + Nitrate II | 2.54 | 2.13 | 1.68 |
| Mean Nitrate I and II | 1.90 | 1.52 | 1.59 |
| HEWL + Nitrate8 | 2.01 | 1.77 | 0.83 |
| HEWL–ascorbate co-crystal | 2.65 | 1.86 | 1.90 |
†
For I/I 0, this is defined as the ratio of D 1/2 (dose to half intensity) with scavenger added to D 1/2 of the native. For the B rel analysis, the enhancement factor is the ratio of ΔB rel/ΔD without scavenger to ΔB rel/ΔD with scavenger (thus a value >1 implies some protection).