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. Author manuscript; available in PMC: 2013 Dec 7.
Published in final edited form as: Cell. 2012 Dec 7;151(6):1185–1199. doi: 10.1016/j.cell.2012.10.047

Figure 5. MYC regulates tumor growth of SIRT6-deficient cells.

Figure 5

A) Western blot showing MYC levels in Sirt6 KO-shVector and shMYC cells. B) 5×105 MEFs were plated in triplicate and cells counted at the indicated time points (error bars indicate SD). C) 5×106 cells of the indicated genotypes were injected into SCID mice and the tumors harvested and weighted (error bars indicate SD). D) Expression of the indicated genes in Sirt6 KO-shVector and KO-shMYC cells (n=9) (error bars indicate SEM). E) Glucose uptake was analyzed in the same cells as in A (error bars indicate SD). F) The same samples as in D were used to analyze the expression of the indicated genes (error bars indicate SEM). See also Figure S5.