Table 3.

Multivariable Cox Regression Analysis of End-Stage Renal Disease after Liver-alone Transplant, Censored for Death^*

Characteristic	Hazard Ratio	Confidence Interval	P
eGFR category
Group 1: eGFR always ≥30 ml/min/m2	Reference	Reference	Reference
Group 2: eGFR fluctuated above and below 30 ml/min/m2	1.66	(1.19, 2.32)	0.003
Group 3: eGFR always <30 ml/min/m2	7.23	(4.08, 12.8)	<0.001
Group 4: Any Dialysis	2.69	(1.55, 4.68)	<0.001
Pre-transplant diabetes	2.65	(1.97, 3.59)	<0.001
Black race versus other	1.83	(1.09, 3.06)	0.021
Male	1.51	(1.11, 2.06)	0.009
Total bilirubin lowest tertile (<2.2 mg/dL)	Reference	Reference	Reference
Total bilirubin middle tertile (2.2–4.4 mg/dL)	0.73	(0.52, 1.02)	0.066
Total bilirubin highest tertile (>4.4 mg/dL)	0.40	(0.25, 0.63)	<0.001
Serum albumin lowest tertile (<2.7 g/dL)	Reference	Reference	Reference
Serum albumin middle tertile (2.7–3.1 g/dL)	0.72	(0.51, 1.02)	0.066
Serum albumin highest tertile (>3.1 g/dL)	0.61	(0.43, 0.88)	0.007
Serum sodium lowest tertile (<134 mEq/L)	Reference	Reference	Reference
Serum sodium middle tertile (134–138 mEq/L)	1.39	(0.96, 2.01)	0.085
Serum sodium highest tertile (>138 mEq/L )	2.40	(1.64, 3.52)	<0.001

^*Model also adjusted for age-strata, pre-transplant hypertension, cause of liver disease, and international normalized ratio of prothrombin time at transplant. None of these variables were significantly associated with the outcome.