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. Author manuscript; available in PMC: 2013 Jun 15.
Published in final edited form as: Bioorg Med Chem. 2012 May 4;20(12):3698–3702. doi: 10.1016/j.bmc.2012.04.056

Figure 3.

Figure 3

At 90 min after injection in controls (open bars) and blocking experiments with the selective α7-nAChRs agonist PHA543613 (0.5 mg/kg, subcutaneous) (black bars), the regional brain uptake of [11C]rac-1 in mice (cerebellum (CB), frontal cortex (FrCtx), hippocampus (Hipp), and the rest of the brain (RB) were compared. There was significant blocking in all regions except cerebellum. Data are mean ± SD. *P < 0.05, significantly different from controls; **P > 0.05, insignificantly different from controls (ANOVA single factor analysis)