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. 2012 Sep 12;38(2):302–312. doi: 10.1038/npp.2012.171

Figure 1.

Figure 1

(a) Increase of basal [35S]guanosine-5′-(γ-thio)triphosphate ([35S]GTPγS) binding to (hD3R)/inducible cell membranes by the agonist quinelorane, alone or in the presence of increasing concentrations of GSK598809. (b) Association of [125I](R)-trans-7-hydroxy-2-[N-propyl-N-(3′-iodo-2′-propenyl)amino] tetralin ([125I]7OH-PIPAT) binding to rD3Rs/stable cell membranes, alone or in the presence of increasing concentrations of GSK598809. (c) Dissociation of [125I]7OH-PIPAT binding to rD3Rs/stable cell membranes induced by the addition of an excess of unlabeled ligand(s).