Table 4.
Effect of orally SA administration for 7 days in biochemical parameters of rat brain antioxidant status
| Treatment | Catalase (U/min) | Superoxide dismutase (U/mg protein) | Glutathione peroxidase assay (nmol/mg protein) |
Glutathione reductase (nmol/min /mg protein) |
Glutathione-S-transferase (nmol/min /mg protein) |
Reduced glutathione (μmol/g tissue) |
Thiobarbituric acid reactive substances (nmol/min / mg protein) |
|---|---|---|---|---|---|---|---|
| Control |
11.0 ± 0.25 |
7.18 ± 2.8 |
43.3 ± 3.58 |
174.5 ± 20.7 |
115.8 ± 26.11 |
64.5 ± 10.7 |
184.5 ± 8.7 |
| SA50 |
15.5 ± 2.8* |
13.5 ± 1.4** |
55.3 ± 1.85* |
203.3 ± 10.3** |
139.8 ± 13.3 * |
88.0 ± 8.3* |
200.3 ± 7.3* |
| SA100 | 14.0 ± 1.12* | 18.3 ± 1.7 ** | 65.3 ± 5.14** | 218.0 ± 10.5 ** | 150.8 ± 11.5** | 91.8 ± 10.0** | 208.0 ± 10.0** |
* p < 0.05 significant difference from control littermates (n = 10/group)
** p < 0.01 significant difference from control littermates (n = 10/group)
The rats brain biochemical parameters are expressed as mean ± S.E.M values