Table 2.
Allele frequencies for all five p21 SNPs in cervical cancer patients and controls
| |
Patient alleles |
control alleles |
|
|
|---|---|---|---|---|
| |
(n = 786) |
(n = 868) |
|
|
| SNP | No. (%) | No. (%) | OR (95% CI) | P* |
| rs762623 |
|
|
|
|
| A |
151 (19.2) |
167 (19.2) |
1.001 (0.782-1.281) |
0.993 |
| G |
635 (80.8) |
701 (80.8) |
|
|
| rs2395655 |
|
|
|
|
| A |
399 (50.8) |
406(46.8) |
1.139 (0.938-1.383) |
0.115 |
| G |
387 (49.2) |
462 (53.2) |
|
|
| rs1801270 |
|
|
|
|
| A |
331 (42.1) |
429 (49.4) |
0.744 (0.613-0.904) |
0.003 |
| C |
455 (57.8) |
439 (50.6) |
|
|
| rs3176352 |
|
|
|
|
| C |
251(31.9) |
317 (41.7) |
0.656 (0.533-0.807) |
0.000 |
| G |
535 (68.1) |
551 (58.3) |
|
|
| rs1059234 |
|
|
|
|
| C |
422 (53.6) |
425 (48.9) |
1.208 (0.996-1.466) |
0.055 |
| T | 364 (46.3) | 443 (51.0) |
* P value was adjusted for age and smoking by multiple logistic regressions. After Bonferroni correction, significant P value was < 0.01.