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BBS mutant mouse SCO ultrastructure. TEM micrographs of coronal sections of 3.5 week-old wild-type (A) and Bbs1M390R/M390R (B) SCO show typical goblet-shaped ependymal cells with intact apical zona adherens junctions between cells (arrows). Single cilia are found on ependymal cell protrusions (arrowheads). The motile cilia seen in cross-section in the lumen of the third ventricle may represent cilia from other SCO cells or from adjacent ventricular ependymal cells.
