Table 1.
Expression data of predicted autophagy genes
| |
|
Identifiers |
|
Expressiona |
|
Fold changeb |
|
FDR q-valuesb |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene | (Predicted) function | S. cerevisiae | A. nidulans | A. niger | Expd | Day 1 | Day 3 | Day 6 | Day 1 | Day 3 | Day 6 | Day 1 | Day 3 | Day 6 | |||
|
atg1 |
Ser/thr kinase |
S000003148 |
AN1632 |
An04g03950 |
|
1.3 |
3.2 |
2.9 |
2.4 |
|
2.4 |
2.2 |
1.8 |
|
2.5E-07 |
1.1E-06 |
1.5E-05 |
|
atg2 |
Membrane protein |
S000005186 |
AN5491 |
An08g10270 |
|
3.9 |
8.2 |
8.2 |
7.8 |
|
2.1 |
2.1 |
2.0 |
|
2.8E-08 |
2.9E-08 |
6.8E-08 |
|
atg3 |
E2-like conjugating enzyme |
S000005290 |
AN11004 |
An03g04380 |
|
1.0 |
2.9 |
2.7 |
2.9 |
|
2.9 |
2.6 |
2.9 |
|
1.8E-08 |
6.1E-08 |
1.9E-08 |
|
atg4 |
Cysteine protease |
S000005167 |
AN3470 |
An11g11320 |
|
4.6 |
15.5 |
16.8 |
17.3 |
|
3.4 |
3.6 |
3.7 |
|
3.8E-10 |
2.1E-10 |
1.6E-10 |
|
atg6 |
Subunit of phosphatidylinositol 3-kinase complexes |
S000006041 |
AN10213 |
An16g07540 |
|
1.0 |
1.0 |
1.0 |
0.8 |
|
1.0 |
1.0 |
0.8 |
|
8.3E-01 |
8.2E-01 |
5.0E-02 |
|
atg7 |
Ubiquitine activating enzyme |
S000001214 |
AN7428 |
An02g14900c |
|
1.5 |
5.6 |
5.1 |
3.0 |
|
3.8 |
3.5 |
2.0 |
|
5.7E-08 |
1.3E-07 |
6.4E-05 |
| |
|
|
|
An02g14910c |
|
6.5 |
20.2 |
18.6 |
15.7 |
|
3.1 |
2.9 |
2.4 |
|
3.7E-10 |
1.1E-09 |
8.3E-09 |
|
atg8 |
Autophagosomal membrane protein |
S000000174 |
AN5131 |
An07g10020 |
|
23.8 |
69.1 |
75.0 |
69.7 |
|
2.9 |
3.2 |
2.9 |
|
3.1E-10 |
1.5E-10 |
3.1E-10 |
|
atg9 |
Transmembrane protein |
S000002308 |
AN3734 |
An06g01500 |
|
1.0 |
8.0 |
6.6 |
5.8 |
|
8.0 |
6.6 |
5.8 |
|
4.1E-11 |
1.3E-10 |
3.0E-10 |
|
atg10 |
E2-like conjugating enzyme |
S000003965 |
AN10728 |
An18g06610 |
|
1.2 |
1.4 |
1.4 |
1.2 |
|
1.1 |
1.2 |
1.0 |
|
1.0E-01 |
3.2E-02 |
7.3E-01 |
|
atg11 |
Adapter protein pexophagy and CVT pathway |
S000006253 |
AN2887 |
An02g07380 |
|
2.3 |
5.2 |
6.1 |
4.0 |
|
2.2 |
2.6 |
1.7 |
|
6.2E-08 |
8.3E-09 |
5.8E-06 |
|
atg12 |
Ubiquitin-like modifier |
S000000421 |
AN1760 |
An11g06920 |
|
0.6 |
0.8 |
0.7 |
0.6 |
|
1.4 |
1.2 |
1.0 |
|
6.4E-03 |
9.4E-02 |
7.9E-01 |
|
atg13 |
Regulatory subunit of Atg1 signalling complex |
S000006389 |
AN2076 |
An11g04460 |
|
0.8 |
1.1 |
1.1 |
1.2 |
|
1.4 |
1.4 |
1.6 |
|
3.3E-02 |
2.0E-02 |
6.6E-03 |
|
atg15 |
Vacuolar lipase |
S000000664 |
AN5919 |
An03g02820 |
|
2.6 |
7.1 |
6.0 |
5.5 |
|
2.7 |
2.3 |
2.1 |
|
5.3E-09 |
4.7E-08 |
1.9E-07 |
|
atg16 |
Atg12-Atg5-Atg16 complex |
S000004769 |
AN0090 |
An18g02220 |
|
1.7 |
3.5 |
3.3 |
2.9 |
|
2.1 |
2.0 |
1.8 |
|
7.1E-05 |
1.1E-04 |
6.7E-04 |
|
atg17 |
Scaffold protein of Atg1 signalling complex |
S000004415 |
AN6360 |
An02g04820 |
|
1.6 |
3.5 |
4.2 |
4.7 |
|
2.2 |
2.7 |
3.0 |
|
8.6E-09 |
9.4E-10 |
2.6E-10 |
|
atg18 |
Phosphoinositide binding protein |
S000001917 |
AN0127 |
An18g03070 |
|
2.0 |
1.8 |
2.8 |
2.6 |
|
0.9 |
1.4 |
1.3 |
|
3.7E-01 |
1.4E-03 |
4.7E-03 |
|
atg20 |
Sorting nexin family member |
S000002271 |
AN6351 |
An02g01390 |
|
4.5 |
7.7 |
8.4 |
9.0 |
|
1.7 |
1.8 |
2.0 |
|
6.1E-06 |
1.1E-06 |
3.3E-07 |
|
atg22 |
Vacuolar integral membrane protein |
S000000543 |
AN7437 |
An02g14810 |
|
5.7 |
10.1 |
9.2 |
8.9 |
|
1.8 |
1.6 |
1.6 |
|
5.3E-07 |
4.0E-06 |
6.8E-06 |
| |
|
|
AN7591 |
An09g03630 |
|
1.6 |
1.4 |
2.0 |
3.1 |
|
0.9 |
1.3 |
2.0 |
|
3.9E-01 |
2.0E-02 |
8.6E-06 |
| |
|
|
AN5876 |
An02g03340 |
|
1.9 |
1.3 |
1.0 |
1.0 |
|
0.7 |
0.5 |
0.6 |
|
8.7E-04 |
3.5E-06 |
1.3E-05 |
|
atg24 |
Sorting nexin |
S000003573 |
AN3584 |
An01g08520 |
|
2.8 |
4.9 |
4.8 |
4.9 |
|
1.7 |
1.7 |
1.7 |
|
2.0E-06 |
3.3E-06 |
2.3E-06 |
|
atg26 |
UDP-glucose:sterol glucosyltransferase |
S000004179 |
AN4601 |
An07g06610 |
|
3.8 |
10.3 |
9.8 |
7.6 |
|
2.7 |
2.6 |
2.0 |
|
2.7E-09 |
5.8E-09 |
2.2E-07 |
|
atg27 |
Type I membrane protein |
S000003714 |
AN0861 |
An01g13390 |
|
1.1 |
1.7 |
1.5 |
1.5 |
|
1.6 |
1.4 |
1.4 |
|
2.8E-06 |
1.8E-04 |
6.8E-05 |
|
atg28 |
Coiled-coil protein |
|
AN1701 |
An04g03260 |
|
1.0 |
1.9 |
1.9 |
2.2 |
|
1.9 |
2.0 |
2.2 |
|
5.9E-06 |
3.7E-06 |
6.5E-07 |
| atg29 | Recruitment of proteins to the pre-autophagosomal structure | S000006087 | AN4832 | An02g13480 | 1.0 | 2.5 | 2.4 | 2.7 | 2.4 | 2.3 | 2.6 | 3.2E-08 | 6.2E-08 | 1.2E-08 | |||
amRNA abundance relative (%) to the gamma-actin (An15g00560) encoding transcript during exponential growth.
bFold changes and FDR q-values for comparisons with transcriptome data from the exponential growth phase.
cORF truncated by contig borders.
dExponential growth phase.