Table 3.
Concordance of HAI definitions, determined by Cohen’s kappa statistic
| Type of HAI or key term | Included cases based on: |
Incidence of HAI (no. cases per 100 patients) | No. cases of HAI |
No. patients without HAI | Cohen’s kappa [95% confidence interval] | ||||
|---|---|---|---|---|---|---|---|---|---|
| US definitions | European definitions | According to either the European or the US definition | According to both the European and the US definitions | According to the European definition but not the US definition | According to the US definition but not the European definition | ||||
| Pneumonia |
PNU1 + PNU2 + PNU3 |
PN1 + PN2 + PN3 + PN4 + PN5 |
2.8 |
180 |
177 |
1 |
2 |
6,326 |
0.99 [0.98 ; 1.00] |
| Clinically defined pneumonia |
PNU1 |
PN2 + PN4 + PN5 |
2.0 |
127 |
102 |
23 |
2 |
6,379 |
0.89 [0.85 ; 0.93] |
| PNU1 |
PN4 + PN5 |
1.8 |
119 |
92 |
15 |
12 |
6,387 |
0.87 [0.82 ; 0.92] |
|
| PNU1* |
PN2 + PN4 + PN5 |
2.0 |
127 |
104 |
21 |
2 |
6,379 |
0.90 [0.86 ; 0.94] |
|
| PNU1* |
PN4 + PN5 |
1.8 |
119 |
94 |
13 |
12 |
6,387 |
0.88 [0.83 ; 0.93] |
|
| Microbiologically defined pneumonia |
PNU2 |
PN1 + PN3 |
1.0 |
65 |
37 |
16 |
12 |
6,441 |
0.72 [0.63 ; 0.82] |
| PNU2 |
PN1 + PN2 + PN3 |
1.2 |
78 |
42 |
29 |
7 |
6,428 |
0.70 [0.60 ; 0.79] |
|
| PNU2† |
PN1 + PN3 |
1.1 |
73 |
53 |
0 |
20 |
6,433 |
0.84 [0.77 ; 0.91] |
|
| PNU2† |
PN1 + PN2 + PN3 |
1.3 |
84 |
60 |
11 |
13 |
6,422 |
0.83 [0.77 ; 0,90] |
|
| ICU-acquired pneumonia |
Pneumonia not present or in incubation at admission |
Pneumonia occurring >48 h after admission |
2.3 |
147 |
144 |
0 |
3 |
28 |
0.94 [0.87 ; 1.00] |
| Mechanical ventilation |
Continuous presence of device within 48 hours preceding pneumonia onset |
Presence of device (even intermittently) within 48 hours preceding pneumonia onset |
2.1 |
136 |
134 |
2 |
0 |
42 |
0.97 [0.93 ; 1.00] |
| Bloodstream infection (BSI) |
Microorganism is not related to infection at another site |
Origin of BSI is “catheter”, “secondary to another site” or “unknown” |
1.9 |
123 |
72 |
51 |
0 |
6,383 |
0.73 [0.66 ; 0.80] |
| Primary BSI |
Microorganism is not related to infection at another site |
Origin of BSI is “catheter” or “unknown” |
1.1 |
72 |
72 |
0 |
0 |
51 |
1.00 |
| ICU-acquired BSI | BSI not present or in incubation at admission | BSI occurring >48 h after admission | 1.5 | 98 | 96 | 0 | 2 | 22 | 0.94 [0.87 ; 1.00] |
*Including PNU3 cases (pneumonia in the immunocompromised patient) qualified as PNU1 after redistribution of PNU3 cases into PNU1 or PNU2.
† Including PNU3 cases (pneumonia in the immunocompromised patient) qualified as PNU2 after redistribution of PNU3 cases into PNU1 or PNU2.