Table 1. Genes up-regulated in daf-10(m79) mutants versus wild-type animals.

Gene	Brief description	p value	Fold change	qRT-PCR data	DAF-16 target?	DAF-12 target?	Pathogen-responsive?	Tissue expression?
F56A4.3	Glutathione-S-tranferase	8.20E-05	18.42	Not repeated
Y19D10A.7/irld-53	EGF receptor, L-domain	5.73E-04	6.44			D*, E		Neuronal (enriched, H)
W02D7.8	Unknown	0.003	4.47					Neuronal (expressed, H)
F14D7.7	Unknown	0.003	4.41
K12G11.3/dod-11 (sodh-1)	Alcohol dehydrogenase	0.006	4.09	Up in osm-5(p813)	A, C		F	Intestinal (expressed, I)
ZC84.3/cls-3	CLASP-family microtubule binding protein	0.006	3.64					Neuronal (enriched, H)
Y19D10A.12/mct-1/2	Monocarboxylate transporter	0.007	3.55	Up in daf-10(m79), down in osm-5(p813)		E
ZK105.5	Unknown, DUF19	0.011	3.26	Not repeated	C
F53A3.1	Unknown	0.016	3.21
F45D11.14	Unknown, DUF684	0.015	3.08
F21C10.11	Unknown	0.016	3.03		C	D*
C09H5.2/catp-3	Cation-transporting ATPase. Regulated by p38 MAP kinase pathway [33]	0.016	2.99	Up in osm-5(p813)
F53B2.2/tsp-4	Tetraspanin family integral membrane protein	0.018	2.98
R08E5.4	Unknown	0.020	2.96		B

A = up-regulated in a daf-16-dependent fashion in daf-2 mutants, Murphy et al., 2003 [31].

B = up-regulated in a daf-16-dependent fashion in daf-2 mutants, McElwee et al., 2004 [35].

C = up-regulated in a daf-16-dependent fashion in daf-2 mutants, Lee et al., 2009 [34].

D* = down-regulated by DAF-12, Fisher and Lithgow, 2006 [30].

E = up-regulated by DAF-12, Shostak et al., 2004 [36].

F = repressed during PA14 exposure, Shapira et al., 2006 [32].

H = Von Stetina et al., 2007 [23].

(“Expressed”: genes whose expression is detected in the neurons, “Enriched”: genes that are solely or more highly expressed in neurons).

I = Pauli et al., 2006 [22].

(“Expressed”: genes whose expression is detected in the intestine, “Enriched”: genes that are solely or more highly expressed in intestine).