Table 1. Clopidogrel treatment prolonged bleeding time without any effect on lipid and blood pressure.

Item		Saline(n = 5)	AngII(n = 11)	AngII+Clog(n = 13)	p
Lipid fractions, mg/dL	Total cholesterol	782.3±48.6	836.2±54.1	789.9±69.7	NS
	Triglycerides	188.4±32.7	188.8±36.9	177.2±15.4	NS
Systolic blood pressure, mm Hg	Before treatment	105.7±6.2	106.3±8.3	105.5±5.9	NS
	After infusion	104.4±6.9	150.4±9.7†	149.3±10†	P<0.05
Bleeding time,second		116.8±31.6	108.9±22.3	>900*	P<0.05
AAA formation, n (%)		None	8 (66.7)	3 (20.0)*	P<0.05
AAA rupture, n (%)		None	5 (62.5)	2 (66.7)	NS

Effect of clopidogrel and angiotensin II (Ang II) on lipid levels, systolic blood pressure and bleeding time in apolipoprotein E (ApoE)-knockout mice.

^†P<0.05 compared with saline infusion or before treatment.

^*P<0.05 compared with control or Ang II-treated only mice.

NS, no significant difference.

Results are mean ± SD.