Skip to main content
. 2012 Dec 20;7(12):e50021. doi: 10.1371/journal.pone.0050021

Figure 5. Confirmatory analysis of BBB breakdown in the anterior ON using low- and high-MW dyes.

Figure 5

A. DAPI-counterstaining of the retina-ON junctional region. The ON and retina (Ret) are indicated. B. Rhodamine-3 kDa dextran label. Strong signal is present only in the anterior ON (the area of infarct; indicated by arrows), and the overlying retina. C. FITC-BSA label. The FITC signal is present in isolated capillaries in the posterior ON (long arrows), as well as a diffuse signal in the infarct region. D. Merged image, showing diffuse dextran-rhodamine and FITC-BSA signal overlap. Scale bar: 50 microns.